Condition: Human Health in Extreme Conditions · Sponsor: University Hospital, Angers
Living for long periods in extreme environments-like Antarctic research stations or space missions-can have a significant impact on human health, especially on the immune system. Scientists have observed that people in such isolated conditions often experience more infections and a reactivation of viruses that usually stay dormant in the body, such as Herpes viruses. These changes affect both parts of the immune system: the rapid-response "innate" system and the slower, more specific "adaptive" system. These immune disruptions may be caused by multiple stressors: ongoing psychological stress, disturbed sleep and light cycles (circadian rhythm disruption), and the challenges of living in confined, isolated, and extreme environments. While space missions and Antarctic overwintering programs have provided some insight into these issues, scientists still lack a detailed understanding of how the immune system adapts-or fails to adapt-over time in such conditions. To help fill this gap, the CHOICE Kerguelen 2 study will follow a group of healthy young adults who will spend one year (from November 2025 to November 2026) in Port-aux-Français, a remote French research station on the Kerguelen Islands in the sub-Antarctic. These volunteers are participating in a civic service program and will be living in a highly isolated environment for the duration of their mission. The CHOICE Kerguelen study is conducted in collaboration with the French Polar Institute (IPEV). The goal of the st…
This description comes directly from the study's public registry record.
Charline MIOT, MD · 02 41 35 36 37 · chmiot@chu-angers.fr
Anthéa LOIEZ · 02 41 35 36 37 · DRCI-Promotion-Interne@chu-angers.fr
Always discuss trial participation with your own doctor first.
| Hôpital SAMUKER, Port-aux-français/ Archipel KERGUELEN /Terres Australes et Antarctiques Françaises | Port-aux-Français, Terres Australes Et Antarctiques Françaises, French Southern and Antarctic Lands | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07275489