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Study identifier: NCT07272239 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Effects of tVNS and mCIMT in Chronic Stroke

Condition: Stroke · Cerebrovascular Accident  ·  Sponsor: Riphah International University

PhaseNA
Planned participants50
Who can joinAll sexes, 50 Years to 75 Years
Healthy volunteersNo

About this study

Stroke is a leading cause of death and disability worldwide, resulting in significant physical and cognitive impairments. Arm weakness is most common after stroke and its treatment is recognized as an area of considerable need. The functional limitations and disabilities experienced by stroke survivors, particularly in the upper limb have a profound impact on their quality of life. Current treatment for arm weakness typically comprises intensive, task-specific and repetitive rehabilitative interventions. Transcutaneous auricular vagus nerve stimulation (tVNS) is a novel noninvasive treatment for stroke that directly stimulates the peripheral auricular branch of the vagus nerve. This study determines the effects of Vagus Nerve Stimulation and Modified Constraint Induced Movement Therapy on Motor Function, Cognition, and Quality of life in chronic stroke patients. This randomized clinical trial will be conducted at IIMCT Railway General Hospital and Al-firdous physiotherapy clinic over a duration of six months. The sample size will consist of 50 participants. Participants which meet the inclusion criteria will be taken through non-probability convenience sampling technique, which will further be randomized through online randomization tool. 25 Participants will be assigned to Group A receiving tVNS and mCIMT with routine physical therapy and 25 to Group B receiving mCIMT with routine physical therapy . Data will be collected using various assessment tools, including Fugl-Meyer…

This description comes directly from the study's public registry record.

Talk to the study team

Zara Mansha, Ms-Nmpt  ·  +923247502192  ·  zaramansha09@gmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

Al- firdous physiotherapy clinicRawalpindi, Punjab Province, PakistanRecruiting
IIMCT- Railway General HospitalRawalpindi, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07272239