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Study identifier: NCT07271966 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

B6 Administration for Levetiracetam-Associated Neurobehavioral Changes and Epilepsy

Condition: Brain Tumor Related Epilepsy (BTRE)  ·  Sponsor: Duke University

PhaseNA
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a supportive care study to assess the effect of Vitamin B6 supplementation on mood-related side effects of levetiracetam in patients with brain tumors, who have already been prescribed levetiracetam for the prevention of seizures. This study will assess this effect from the perspective of both the patient and the patient's caregiver. Patients will receive Vitamin B6 as a supplement to take daily for 8 to 12 weeks, in addition to the already prescribed levetiracetam and will undergo study assessments as well as complete self-reported questionnaires to evaluate their mood during the course of the study. Additionally, each patient will be asked to optionally identify a designated caregiver, who will complete questionnaires assessing the patient's mood changes, at the same time interval as the patient.

This description comes directly from the study's public registry record.

Talk to the study team

Katherine Peters, MD, PhD  ·  919-684-5301  ·  dukebrain1@duke.edu

Stevie Threatt, MS  ·  919-684-5301  ·  dukebrain1@duke.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Duke University Medical CenterDurham, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07271966