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Study identifier: NCT07271342 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Observational RegIstry of Effectiveness and Safety of teNecTeplase in reAl worLd Settings in China

Condition: Stroke  ·  Sponsor: Beijing Tiantan Hospital

PhaseN/A
Planned participants10000
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The ORIENTAL study is a prospective, multicenter, continuously enrolled real-world cohort designed to evaluate the effectiveness and safety of intravenous tenecteplase for acute ischemic stroke (AIS) in routine clinical practice across China. Approximately 10,000 patients from about 200 hospitals will be included. Eligible adults with imaging-confirmed AIS who receive tenecteplase as part of standard care will be consecutively enrolled and followed through 90 days. The study will describe patient characteristics, treatment processes, functional outcomes, and safety events, and will also explore inter-hospital variability and subgroup differences to support quality improvement and guide nationwide implementation of tenecteplase therapy.

This description comes directly from the study's public registry record.

Talk to the study team

Yongjun Wang, MD  ·  86-10-59978350  ·  yongjunwang@ncrcnd.org.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Beijing Tiantan Hospital, Capital Medical UniversityBeijing, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07271342