Condition: MDD · Severe Depression · Major Depressive Episode · Sponsor: Technical University of Munich
The primary purpuse of this pilot study is to find out whether a home-based transcranial direct current stimulation (tDCS) program is feasible and well tolerated as maintenance therapy and whether there are early signs that it helps maintain the clinical clinical benefits achieved during successful acute inpatient treatment. Participant population: Adults (18+) with depressive disorder who had already improved/stabilized after acute treatment at our clinic (esketamine, repetitive transcranial magnetic stimulation , or electroconvulsive therapy). Main questions: Feasibility: Do participants reliably complete the home program and stay in the study? Preliminary effectiveness: Do improvements of depressive symptoms hold up over the 4-week treatment and 2-week follow-up (based on self-report and clinician-rated scales)? Participants receive standardized instruction from trained staff and a portable tDCS device (with cap and small sponge electrodes) and complete 20 home sessions over 4 weeks (5 per week), each 30 minutes at a very low current (2 mA); the device gently ramps current up/down for comfort. During treatment, participants use a smartphone app with step-by-step guidance and reminders; sessions are automatically logged. They will also fill out short weekly self-rating questionnaires and join brief phone check-ins every 2 weeks. Where: Department and Outpatient Clinic of Psychiatry and Psychotherapy, Klinikum rechts der Isar, Technical University of Munich Safety …
This description comes directly from the study's public registry record.
Ulrike Vogelmann, Dr. med. · +4917661535471 · ulrike.vogelmann@mri.tum.de
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| Technical University of Munich, TUM School of Medicine and Health, Department of Psychiatry and Psychotherapy, Munich, | München, Bavaria, Germany | Enrolling By Invitation |
| Department of Psychiatry and Psychotherapy, Technical University of Munich, University Hospital | München, Germany | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07269964