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Study identifier: NCT07269223 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Oral Vitamin D3 Effect on Inflammatory Biomarkers in Ulcerative Colitis Patients

Condition: Ulcerative Colitis (UC)  ·  Sponsor: University of Veterinary and Animal Sciences, Lahore - Pakistan

PhaseNA
Planned participants60
Who can joinAll sexes, 20 Years to 40 Years
Healthy volunteersNo

About this study

This randomized controlled trial aims to evaluate the effect of oral vitamin D3 supplementation on inflammatory biomarkers and disease activity in Pakistani patients with moderate ulcerative colitis. Sixty patients will be randomized to receive either standard treatment alone/Placebo or standard treatment plus vitamin D3 (50,000 IU fortnightly) for 12 weeks. Primary outcomes include changes in blood (CRP, ESR, IL-6) and fecal (calprotectin) inflammatory biomarkers, and disease activity assessed by the partial Mayo score. Secondary outcomes include vitamin D status, dietary intake, and quality of life. The study will provide insights into the immune-modulating and anti-inflammatory role of vitamin D3 as an adjunct therapy in ulcerative colitis.

This description comes directly from the study's public registry record.

Talk to the study team

Muhammad Barkaat Azam, PhD Scholar  ·  923336654554  ·  barkaatazam@gmail.com

Dr. Qaisar Raza, PhD  ·  923002479044  ·  qaisar.raza@uvas.edu.pk

Always discuss trial participation with your own doctor first.

Locations (1)

University of Veterinary & Animal Sciences, LahoreLahore, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07269223