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Study identifier: NCT07269106 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Efficacy and Safety of Anrikefon for Postoperative Analgesia in Ophthalmic Surgery

Condition: Ophthalmic Surgery · Postoperative Pain Management · Opioid Analgesia  ·  Sponsor: Zhongshan Ophthalmic Center, Sun Yat-sen University

PhasePhase 4
Planned participants204
Who can joinAll sexes, 18 Years to 70 Years
Healthy volunteersNo

About this study

The goal of this clinical trial is to learn if Anrikefon works as well as nalbuphine to control postoperative pain in adults undergoing ophthalmic surgery under general anesthesia. It will also learn about the safety and recovery outcomes of using Anrikefon. The main questions it aims to answer are: * Does Anrikefon provide pain relief that is not inferior to nalbuphine after ophthalmic surgery? * Does Anrikefon cause fewer central side effects, such as sedation or dizziness, compared with nalbuphine? * Does Anrikefon help patients recover and get discharged faster after day-surgery procedures? Researchers will compare Anrikefon to nalbuphine to see if Anrikefon can offer effective and safer perioperative analgesia for ophthalmic day-surgery patients. Participants will: * Receive either an intravenous dose of Anrikefon or nalbuphine during surgery. * Be monitored for pain scores, side effects, and recovery parameters after surgery. * Complete follow-up assessments.

This description comes directly from the study's public registry record.

Talk to the study team

Xiaoliang Gan, PhD  ·  0086-13688893908  ·  ganxl@mail.sysu.edu.cn

Yanling Zhu, MD  ·  0086-18898600243  ·  zhuyling8@mail.sysu.edu.cn

Always discuss trial participation with your own doctor first.

Locations (3)

Zhongshan Ophthalmic Center, Sun Yat-Sen UniversityGuangzhou, Guangdong, ChinaRecruiting
The Affiliated Hospital of Yunnan UniversityKunming, Yunnan, ChinaNot Yet Recruiting
Eye & ENT Hospital of Fudan UniversityShanghai, ChinaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07269106