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Study identifier: NCT07268768 Synced from ClinicalTrials.gov · July 28, 2026
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PERSONOLOGICAL STRUCTURE, COGNITIVE FUNCTIONS AND CENTRAL SENSITIZATION IN HEADACHE

Condition: Chronic and Episodic Headache · Headache Disorders  ·  Sponsor: IRCCS Centro Neurolesi Bonino Pulejo

PhaseN/A
Planned participants64
Who can joinAll sexes, 18 Years to 60 Years
Healthy volunteersNo

About this study

Headache, in its episodic and chronic forms, cannot be considered solely as an isolated neurological symptom, but as a complex condition of a bio-psycho-social nature. While in the episodic form the painful episodes occur intermittently and have a variable impact on daily life, in the chronic form the disease evolves towards persistent pain, with more significant consequences on personal, social and work functioning. The following study protocol aims to investigate in an integrated manner the neurological, cognitive and psychological mechanisms involved in headache, with particular attention to the differences between episodic and chronic forms. The main objective is to assess the neuropsychological profiles and pain response of patients, monitoring their evolution over a period of approximately six months, considering the impact of central sensitisation, personality structure and any psychopathological comorbidities on pain management and treatment adherence. The protocol adopts a multidimensional approach aimed at optimising therapeutic efficacy and improving patients' quality of life, preventing progression to chronicity.

This description comes directly from the study's public registry record.

Talk to the study team

Anna Anselmo, Psychologist  ·  3489266543  ·  anna.anselmo@irccsme.it

Always discuss trial participation with your own doctor first.

Locations (1)

Irccs Centro Neurolesi Bonino PulejoMessina, Sicily, ItalyRecruiting

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Source record: clinicaltrials.gov/study/NCT07268768