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Study identifier: NCT07268638 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Praliciguat in Participants With Focal Segmental Glomerulosclerosis (FSGS)

Condition: Focal Segmental Glomerulosclerosis  ·  Sponsor: Akebia Therapeutics

PhasePhase 2
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 2, randomized, double-blind, placebo-controlled, multicenter study designed to evaluate the efficacy and safety of praliciguat in adults with biopsy-confirmed focal segmental glomerulosclerosis (FSGS). Participants will be randomized 1:1 to receive praliciguat or placebo for initial 24 week treatment period. Following this double-blind period, all participants will receive praliciguat in an open-label extension for an additional 24 weeks.

This description comes directly from the study's public registry record.

Talk to the study team

Akebia Therapeutics  ·  16178446128  ·  trials@akebia.com

Always discuss trial participation with your own doctor first.

Locations (23)

Investigator Site #2Chula Vista, California, United StatesRecruiting
Investigator Site #14Los Angeles, California, United StatesRecruiting
Investigator Site #12San Dimas, California, United StatesRecruiting
Investigator Site #13Arvada, Colorado, United StatesRecruiting
Investigator Site #17Boca Raton, Florida, United StatesRecruiting
Investigator Site #6Coral Springs, Florida, United StatesRecruiting
Investigator Site #7Miami, Florida, United StatesRecruiting
Investigator Site #8Orlando, Florida, United StatesRecruiting
Investigator Site # 1Lawrenceville, Georgia, United StatesRecruiting
Investigator Site #3Chicago, Illinois, United StatesTerminated
Investigator Site #11Louisville, Kentucky, United StatesRecruiting
Investigator Site #15Livonia, Michigan, United StatesRecruiting

+ 11 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07268638