Condition: Pancreatitis, Acute · Sponsor: Efferon JSC
The goal of the study is to evaluate the safety and efficacy of multimodal (cytokine and lipopolysaccharide) hemoperfusion using the Efferon® LPS device in combination with hemofiltration (HF) / hemodiafiltration (HDF), with the goal of reducing the severity of organ dysfunction (measured by SOFA score) in patients with acute pancreatitis. Participants will be assigned to two groups for comparison: a control group receiving baseline therapy with HF/HDF, and a treatment group receiving baseline therapy in combination with HF/HDF and Efferon® LPS hemoadsorption.The therapy will be initiated within the first 24 hours after ICU admission and within 8 hours after patient enrollment.
This description comes directly from the study's public registry record.
Alexandr Shelehov-Kravchenko, PhD, MD · +79636564765 · alexandr.shelehov@gmail.com
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| Republican Clinical Hospital of the Ministry of Health of the Republic of Tatarstan | Kazan', Russia | Recruiting |
| State Clinical Hospital "Regional Clinical Hospital No 2" of the Ministry of Healthcare of Krasnodar Territory | Krasnodar, Russia | Recruiting |
| V.P. Demikhov City Clinical Hospital No. 68 | Moscow, Russia | Recruiting |
| S.S. Yudin City Clinical Hospital | Moscow, Russia | Recruiting |
| N.I. Pirogov City Clinical Hospital No. 1 | Moscow, Russia | Recruiting |
| N.V. Sklifosovsky Research Institute for Emergency Medicine | Moscow, Russia | Recruiting |
| Perm regional clinical hospital | Perm, Russia | Recruiting |
| North-Western district scientific and clinical center named after L. G. Sokolov Federal Medical and Biological Agency | Saint Petersburg, Russia | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07267169