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Study identifier: NCT07266805 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Study of Oral Deucrictibant XR Tablet for Prophylaxis and Deucrictibant IR Capsule for On-Demand Treatment of Angioedema Attacks in Adults With Acquired Angioedema Due to C1 Inhibitor Deficiency

Condition: Acquired Angioedema Due to C1-Inhibitor Deficiency (AAE-C1-INH)  ·  Sponsor: Pharvaris Netherlands B.V.

PhasePhase 3
Planned participants32
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 3, multicenter, 3-part study, with 2 randomized, double-blind, placebo-controlled parts and an open-label extension part, to evaluate the efficacy and safety of orally administered deucrictibant XR tablet for prophylaxis, and deucrictibant IR capsule for on-demand treatment of angioedema attacks in adult participants aged ≥ 18 years with AAE-C1INH.

This description comes directly from the study's public registry record.

Talk to the study team

Pharvaris Clinical Team  ·  0031-712-036-410  ·  clinicaltrials@pharvaris.com

Always discuss trial participation with your own doctor first.

Locations (32)

Study SiteSan Diego, California, United StatesRecruiting
Study SiteWalnut Creek, California, United StatesRecruiting
Study SiteSt Louis, Missouri, United StatesRecruiting
Study SiteHershey, Pennsylvania, United StatesRecruiting
Study SiteClayton, AustraliaRecruiting
Study SiteVienna, AustriaRecruiting
Study SiteSofia, BulgariaRecruiting
Study SiteEdmonton, CanadaRecruiting
Study SiteGrenoble, FranceRecruiting
Study SiteLille, FranceRecruiting
Study SiteParis, FranceRecruiting
Study SiteBerlin, GermanyRecruiting

+ 20 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07266805