Condition: Refractory Membranous Nephropathy · Sponsor: The First Affiliated Hospital of Air Force Medicial University
This study is a single-center, prospective, exploratory Phase I clinical trial initiated by the team led by Associate Professor He Lijie from the Department of Nephrology, Xijing Hospital. Prior to receiving CAR-T cell therapy, patients will undergo lymphodepletion chemotherapy with cyclophosphamide (fludarabine will be added if necessary). After prophylactic administration of antihistamines and acetaminophen, patients will be infused with CD19 CAR-T cells at a dose of 1×10⁶ cells/kg. In the subsequent 2 weeks, patients will be hospitalized for monitoring of vital signs and adverse reactions. The planned follow-up duration of this study is 1 years.
This description comes directly from the study's public registry record.
Jipeng Li · 8684775197 · shaona@ldy.edu.rs
Always discuss trial participation with your own doctor first.
| Department of Nephrology, Xijing Hospital | Xi'an, China, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07266181