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Study identifier: NCT07265544 Synced from ClinicalTrials.gov · July 28, 2026
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Single-cell Multiomics and Spatiotemporal Omics Analyze the Mechanism of Liver Degenerative Disease

Condition: Liver Neoplasm · HBV Infection · Non-alcoholic Fatty Liver Disease NAFLD  ·  Sponsor: Nanfang Hospital, Southern Medical University

PhaseN/A
Planned participants240
Who can joinAll sexes, N/A to no upper limit
Healthy volunteersYes

About this study

The purpose of this observational study is to employ single-cell multi-omics and spatial omics technologies to characterize the spatial and immune structures within the livers of patients with fatty liver, hepatic hemangioma, focal nodular hyperplasia, liver fibrosis, cirrhosis, and HBV infection. The primary questions it aims to address are: Investigate the mechanisms of liver degenerative changes during the processes of liver aging, fatty liver, HBV infection, liver fibrosis, and cirrhosis. Characterize the molecular features and cellular networks at different stages of liver degeneration and identify new targets and mechanisms for the cure of the aforementioned diseases. The study will collect peripheral blood and discarded liver tissue from patients with hepatic hemangioma, fatty liver, HBV infection, liver fibrosis, and cirrhosis who are undergoing hepatectomy or liver biopsy.

This description comes directly from the study's public registry record.

Talk to the study team

Yongyin Li, Dr.  ·  +8613826039505  ·  yongyinli@foxmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

NanGuangzhou, Guangdong, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07265544