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Study identifier: NCT07264959 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

An Observational Study in Participants With Indolent Systemic Mastocytosis (ISM)

Condition: Indolent Systemic Mastocytosis  ·  Sponsor: Blueprint Medicines Corporation

PhaseN/A
Planned participants150
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a Phase 4, non-interventional, observational study to collect detailed data on the clinical characteristics, clinical outcomes and medical management of ISM in real-world settings. The study will describe the demographic and clinical characteristics of ISM participants, including anaphylaxis and bone manifestations in ISM. Quality of life and disease control will be assessed through participant questionnaires. The study will also evaluate real world ISM treatment management, including use of avapritinib.

This description comes directly from the study's public registry record.

Talk to the study team

Blueprint Medicines  ·  1-888-258-7768  ·  medinfo@blueprintmedicines.com

Blueprint Medicines, EU Contact  ·  +31 85 064 4001  ·  medinfoeurope@blueprintmedicines.com

Always discuss trial participation with your own doctor first.

Locations (1)

Brigham and Women's Allergy and Clinical Immunology, Mass General Brigham Healthcare Center (Chestnut Hill)Chestnut Hill, Massachusetts, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07264959