Condition: Periodontis · Atherosclerosis Cardiovascular Disease · Sponsor: Nantes University Hospital
Periodontal diseases are chronic inflammatory conditions affecting nearly half of the adult population and are associated with systemic inflammatory responses. Recent evidence suggests a possible link between severe periodontitis and cardiovascular diseases through shared inflammatory pathways. The PAROCAR study aims to evaluate the association between generalized periodontitis (stages 3 and 4, 2017 Chicago Classification) and arterial stiffness measured by pulse wave velocity (PWV), compared to matched controls without periodontitis, adjusted for conventional cardiovascular risk factors.
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| CHU de Nantes | Nantes, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07263113