Condition: Heart Failure · Heart Failure - NYHA II - IV · Heart Failure Acute · Sponsor: Lakeland Regional Health Systems, Inc.
The goal of this clinical trial is to learn if increasing the dose of diuretics to achieve a higher urine sodium target produces better clinical results when treating patients hospitalized with acute heart failure when compared to lower urine sodium target and standard of care. The main questions it aims to answer are: 1. Does targeting a higher urine sodium goal achieve greater natriuresis and diuresis? 2. Does targeting a higher urine sodium goal reduce frequency of hospital readmissions? 3. Does targeting a higher urine sodium goal reduce hospital length of stay? Researchers will compare natriuresis-guided arms with standard of care to see if targeting higher natriuresis goals improves significantly over current practice. Participants will submit urine samples at routine intervals after being given diuretics to evaluate urine sodium concentration. If urine sodium is low then diuretic dose will be increased.
This description comes directly from the study's public registry record.
Andrew Lurie, DO · 8636871100 · Andrew.Lurie@myLRH.org
Anas Bizanti, MD · 8636871100 · anas.bizanti@mylrh.org
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| Lakeland Regional Hospital | Lakeland, Florida, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07263035