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Study identifier: NCT07262567 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Phase III Study to Compare GFH375 and Chemotherapy in Patients With KRAS G12D-Mutant Metastatic Pancreatic Cancer

Condition: Metastatic Pancreatic Cancer  ·  Sponsor: Genfleet Therapeutics (Shanghai) Inc.

PhasePhase 3
Planned participants320
Who can joinAll sexes, 18 Years to 80 Years
Healthy volunteersNo

About this study

This study plans to enroll participants with previously treated metastatic pancreatic cancer and harbor centrally confirmed KRAS G12D mutation. These participants are required to experience disease progression on or after at least one prior standard systemic therapy containing fluorouracil or gemcitabine, and either progressed on or were intolerant to the last treatment. Eligible participants will be randomized 1:1 to the experimental group or the control group for treatment.

This description comes directly from the study's public registry record.

Talk to the study team

Jin Li  ·  +86 21 6882 1388  ·  jli@genfleet.com

Always discuss trial participation with your own doctor first.

Locations (1)

Peking University Cancer Hospital & InstituteBeijing, Beijing Municipality, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07262567