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Study identifier: NCT07262138 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Active Surveillance in Older Women With ER+ Breast Cancer

Condition: Early Stage Estrogen Receptor (ER) Positive Breast Cancer  ·  Sponsor: University of Pittsburgh

PhaseN/A
Planned participants50
Who can joinFemale, 70 Years to no upper limit
Healthy volunteersNo

About this study

ACTIVE is a prospective, single-arm, phase I/IIa study examining an active surveillance strategy for small, screen-detected, luminal breast cancer. Patients aged 70 or older with clinical stage I ER+/HER2- breast cancer are eligible. The goal of this clinical trial is to learn if an active surveillance strategy (serial imaging rather than therapeutic intervention) is a safe approach to monitor small breast cancers. The main question to answer is the proportion of participants who experience tumor progression by 12 months.

This description comes directly from the study's public registry record.

Talk to the study team

Neil Carleton, MD, PhD  ·  412-266-1991  ·  carletonn2@upmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Pittsburgh Medical CenterPittsburgh, Pennsylvania, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07262138