Condition: Primary Progressive Aphasia(PPA) · Progressive Aphasia · Progressive Aphasia in Alzheimer's Disease · Sponsor: Maya Henry
The goal of this clinical trial is to learn whether home-based brain stimulation combined with virtual speech-language therapy can improve communication abilities in adults with logopenic variant primary progressive aphasia (lvPPA), a language disorder most often caused by Alzheimer's disease. The main questions the study aims to answer are: * Is combining remotely supervised transcranial direct current stimulation (tDCS) with virtual speech-language therapy feasible and acceptable for people with lvPPA? * Does this combined treatment lead to improvements in communication compared to speech-language therapy with sham (placebo) stimulation? * Do individual brain characteristics help predict who benefits most from this treatment? Researchers will compare participants who receive active tDCS plus virtual speech-language therapy to participants who receive sham (placebo) tDCS plus virtual speech-language therapy to see if active brain stimulation enhances communication outcomes. Participants will: * Complete speech-language therapy sessions delivered by video visit. * Receive either active or sham tDCS that is remotely supervised and completed at home. * Complete language and cognitive testing before and after treatment. * Undergo brain imaging and other assessments to help understand treatment response.
This description comes directly from the study's public registry record.
Aphasia Lab Research Coordinator · 512-471-3420 · aphasialab@austin.utexas.edu
Always discuss trial participation with your own doctor first.
| UCSF Memory and Aging Cener | San Francisco, California, United States | Recruiting |
| University of Texas | Austin, Texas, United States | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07260253