Condition: DLBCL · CLL · Sponsor: Institute of Hematology & Blood Diseases Hospital, China
The aim of this study is to analyze the safety of BAFF-R Chimeric Antigen Receptor T-Cell Injection (BAFF-R CAR-T) in participants with relapsed/refractory BAFF-R-positive B-cell lymphoma and explore the Maximum Tolerated Dose (MTD). The secondary objective of this study is to explore the efficacy of BAFF-R CAR-T in participants with relapsed/refractory BAFF-R-positive B-cell lymphoma. The study also aims to explore the pharmacokinetic characteristics of BAFF-R CAR-T in vivo and the impact of BAFF-R CAR-T on lymphocyte subsets in vivo.
This description comes directly from the study's public registry record.
Shuhua Yi,Dr · 86-22-23608109 · yishuhua@ihcams.ac.cn
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| Institute of Hematology and Blood Diseases Hospital ,Chinese Academy of Medical Sciences | Tianjin, Tianjin Municipality, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07259070