Condition: Plasmodium Vivax Infection · Sponsor: University of Oxford
This study is a human challenge study to assess the minimum infective mosquito bite dose in a controlled human malaria Infection (via P. vivax sporozites) in healthy volunteers. The results will inform the development of a P. vivax mosquito-delivered CHMI trial platform, supporting safer and more accurate vaccine efficacy assessments. Conducting the trial in individuals genetically and immunologically similar to the target population will also enhance the relevance of findings to real-world endemic settings. This study is funded by the UK Wellcome Trust. The grant reference number are Oxford/MORU: 212336/Z/18/Z and 212336/Z/18/A, and Mahidol University: 212336/A/18/Z and 212336/A/18/A.
This description comes directly from the study's public registry record.
Nicholas Day, MD · +66-(0)2-3549170 · nickd@tropmedres.ac
Jetsumon Sattabongkot Prachumsri, Ph.D · +66-(0)2-3549100 · jetsumon.pra@mahidol.ac.th
Always discuss trial participation with your own doctor first.
| Faculty of Tropical Medicine, Mahidol University | Bangkok, Thailand | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07257965