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Study identifier: NCT07256301 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Phase Ib, Multicenter, Open-Label Study of Multiple-Dose EA5 in Adults With Paroxysmal Nocturnal Hemoglobinuria (PNH)

Condition: PNH - Paroxysmal Nocturnal Hemoglobinuria  ·  Sponsor: Shanghai Lanyi Therapeutics Co., Ltd.

PhasePhase 1
Planned participants24
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a multicenter, open-label, Phase Ib clinical trial designed to evaluate the safety, pharmacokinetics (PK), and pharmacodynamics (PD) of multiple doses of the humanized monoclonal antibody EA5 in adult patients with paroxysmal nocturnal hemoglobinuria (PNH).

This description comes directly from the study's public registry record.

Talk to the study team

Fengkui zhang, Dr.  ·  +86-022-23909999  ·  zhfk@hotmail.com

Always discuss trial participation with your own doctor first.

Locations (2)

The Institute of Hematology & Blood Diseases Hospital (Chinese Academy of Medical Sciences)Tianjin, Tianjin Municipality, ChinaRecruiting
The First Affiliated Hospital, Zhejiang University School of Medicine, Chengzhan CampusHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07256301