Condition: Circulatory Failure / Shock State · Fluid Therapy · Sponsor: University Hospital, Bordeaux
The investigators aim to validate markers of metabolic fluid-responsiveness in children with acute circulatory failure following cardiac surgery. This would allow physicians to identify which patient could benefit the most from fluid expansion, thus avoiding useless and potentially dangerous fluid expansions that could lead to fluid overload. To this end, The investigators will evaluate the diagnostic accuracy of the ratio of central venous to arterial carbon dioxide tension (Pv-aCO2) to arteriovenous oxygen content (CavO2), a simple biological marker of anaerobic metabolism, for the diagnosis of metabolic fluid responsiveness defined as a significant increase in oxygen consumption (VO2) after fluid expansion.
This description comes directly from the study's public registry record.
Julin GOTCHAC, MD · +33 5 24 54 92 19 · julien.gotchac@chu-bordeaux.fr
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| Hôpital Louis Pradel - Hospices Civils de Lyon | Bron, France, France | Recruiting |
| Hôpital Jeanne de Flandre - CHU de Lille | Lille, France, France | Recruiting |
| Hôpital de la Timone - Assistance Publique - Hôpitaux de Marseille | Marseille, France, France | Not Yet Recruiting |
| Hôpital mère-enfant - CHU de Nantes | Nantes, France, France | Recruiting |
| Hôpital Necker-Enfants Malades - Assistance Publique - Hôpitaux de Paris | Paris, France, France | Recruiting |
| Hôpital Cardiologique Haut Lévêque - CHU de Bordeaux | Pessac, France, France | Recruiting |
| Hôpital des enfants - CHU de Toulouse | Toulouse, France, France | Not Yet Recruiting |
| Hôpital Felix Guyon - CHU de la Réunion | Saint-Denis, La Réunion, France | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07255469