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Study identifier: NCT07255378 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Use of Vassopresin in Septic Shock Prospective Multicenter Observational Study With Medication

Condition: Septic Shock  ·  Sponsor: Jamil Cedeño Mora

PhaseN/A
Planned participants1200
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The aim of this observational study is to examine real-world clinical practice regarding the use of vasopressin as a second-line vasopressor in adult patients admitted to Intensive Care Units (ICUs) with septic shock. The study focuses on critically ill adults (≥18 years) diagnosed with septic shock and treated with norepinephrine and vasopressin. The main research questions are: * Does early initiation of vasopressin-defined by the norepinephrine dose at the time of introduction-reduce mortality in patients with septic shock? * What is the impact of vasopressin as a second vasopressor on renal function and the progression of organ dysfunction in septic shock patients? Participants will: * Be admitted to an ICU with a diagnosis of septic shock. * Receive vasopressin as an adjunct to norepinephrine for hemodynamic support. * Be monitored daily throughout their ICU stay, with data collected through a dedicated REDCap system. * Have relevant clinical data pseudonymized and incorporated into the study database for statistical analysis.

This description comes directly from the study's public registry record.

Talk to the study team

Jamil Antonio Cedeño Mora  ·  +34 630 03 65 02  ·  jamilantonio.cedeno@salud.madrid.org

Always discuss trial participation with your own doctor first.

Locations (12)

Consorci Sanitari de TerrassaTerrassa, BARCELONA, SpainRecruiting
Hospital Universitario de GetafeGetafe, Madrid, SpainRecruiting
Hospital Universitario La PrincesaMadrid, Madrid, SpainRecruiting
Hospital General Universitario Gregorio MarañónMadrid, Madrid, SpainRecruiting
Hospital Universitario Ramón y CajalMadrid, Madrid, SpainRecruiting
Hospital Universitario Clínico San CarlosMadrid, Madrid, SpainRecruiting
Hospital Universitario Doce de OctubreMadrid, Madrid, SpainRecruiting
Hospital Universitario La PazMadrid, Madrid, SpainRecruiting
Hospital Universitario Puerta de HierroMajadahonda, Madrid, SpainRecruiting
Hospital Universitario Rey Juan CarlosMóstoles, Madrid, SpainRecruiting
Hospital Universitario y Politécnico de La FeValencia, Valencia, SpainRecruiting
Hospital Universitario Miguel ServetZaragoza, ZARAGOZA, SpainRecruiting

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Source record: clinicaltrials.gov/study/NCT07255378