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Study identifier: NCT07253857 Synced from ClinicalTrials.gov · July 28, 2026
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Effects of Hand and Arm Bimanual Intensive Therapy Including Lower Extremity in Spastic Cerebral Palsy

Condition: Cerebral Palsy · Cerebral Palsy, Spastic  ·  Sponsor: Lahore University of Biological and Applied Sciences

PhaseNA
Planned participants42
Who can joinAll sexes, 6 Years to 12 Years
Healthy volunteersNo

About this study

Cerebral palsy (CP), particularly the spastic diplegic subtype, is characterized by motor impairments such as spasticity and mobility limitations. In addition to motor dysfunction, children with CP often experience cognitive impairments affecting decision-making, problem-solving, working memory, selective attention, and inhibitory control. These non-motor challenges contribute to reduced social interaction and quality of life. Hand-Arm Bimanual Intensive Therapy Including Lower Extremity (HABIT-ILE) has demonstrated improvements in gross motor function among children with spastic CP. However, evidence regarding its impact on cognitive outcomes remains limited. This randomized controlled trial (RCT) aims to evaluate the effects of HABIT-ILE compared with conventional therapy on both motor and cognitive functions in children with spastic diplegic CP. By addressing both upper and lower limb the research seeks to provide a comprehensive therapeutic approach that may yield more significant developmental benefits. Ultimately, the findings could inform the interventions for improving outcomes in pediatric populations affected by diplegic cerebral palsy. Participants will receive 90 hours of intervention, with assessments conducted at baseline, mid-intervention, and post-intervention. The study will investigate outcomes across motor domains and cognitive functions such as inhibitory control and working memory. Findings are expected to inform comprehensive therapeutic approaches to …

This description comes directly from the study's public registry record.

Talk to the study team

Aleena Ishfaq, DPT  ·  +92 3324210141  ·  draleenaishfaqpt@gmail.com

Aruba Saeed, NMPT, PhD*  ·  +92 3344399403  ·  aruba.saeed@ubas.edu.pk

Always discuss trial participation with your own doctor first.

Locations (1)

Pakistan Society for Rehabilitation of Differently Abled (PSRD)Lahore, Punjab Province, PakistanRecruiting

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Source record: clinicaltrials.gov/study/NCT07253857