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Study identifier: NCT07253285 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Research Study on How Well Cagrilintide and CagriSema Work in Children and Adolescents With Excess Body Weight

Condition: Overweight · Obesity  ·  Sponsor: Novo Nordisk A/S

PhasePhase 3
Planned participants460
Who can joinAll sexes, 8 Years to 18 Years
Healthy volunteersNo

About this study

This study will look at how well CagriSema and cagrilintide help children and adolescents with excess body weight lose weight. The study has 2 parts: main and extension study. In the main study, participants will either get CagriSema (a new study drug), cagrilintide (a new study drug), semaglutide (a drug that doctors can already prescribe to adolescents and adults) or placebo (a placebo looks like the treatment being tested, but doesn't have any active ingredients in it). Which treatment participants will get is decided by chance. Participants who get semaglutide in the main study will not take part in the extension study. If participants take part in the extension study, they will get either CagriSema or cagrilintide in this part of the study. Like all drugs, the study drugs may have side effects. The total time participants will be in the main study is about 1 year and 6 months. If participants take part in the extension study, the total time is about 4 years and 10 months.

This description comes directly from the study's public registry record.

Talk to the study team

Novo Nordisk  ·  (+1) 866-867-7178  ·  clinicaltrials@novonordisk.com

Always discuss trial participation with your own doctor first.

Locations (120)

Neighborhood HealthcareEscondido, California, United StatesNot Yet Recruiting
Encore Medical Research LLCHollywood, Florida, United StatesRecruiting
Jacksonville Ctr for Clin ResJacksonville, Florida, United StatesNot Yet Recruiting
Encore Medical Research of WestonWeston, Florida, United StatesRecruiting
Children's Healthcare AtlantaAtlanta, Georgia, United StatesRecruiting
Columbus Research FoundationColumbus, Georgia, United StatesRecruiting
Accel Research Sites-NeuroStudiesDecatur, Georgia, United StatesRecruiting
Eastside Bariatric and Gen SurgSnellville, Georgia, United StatesRecruiting
Solaris Clinical ResearchMeridian, Idaho, United StatesNot Yet Recruiting
IU Health - Riley Physicians Endo-DiabIndianapolis, Indiana, United StatesRecruiting
Cotton O'Neil Clinical Research CenterTopeka, Kansas, United StatesNot Yet Recruiting
Pennington Biomed Res CtrBaton Rouge, Louisiana, United StatesRecruiting

+ 108 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07253285