Condition: Acute Ischemic Stroke · Large Vessel Occlusion · Transportation of Patients · Sponsor: Xuanwu Hospital, Beijing
This study will address the efficacy and safety of Tenecteplase administered in non-endovascular capable center (nECC) in patients with acute ischemic stroke (AIS) caused by anterior circulation large vessel occlusion (acLVO) who present in the 4.5- to 24-hour time window before interhospital transfer to an endovascular capable center (ECC) for endovascular treatment (EVT). * Primary objective: To evaluate the efficacy and safety of Tenecteplase administration at a nECC before EVT transfer compared with standard of care * Secondary objective: To evaluate the impact of time from needle-to-arterial puncture on clinical outcomes Patients who meet inclusion criteria will be randomized to Tenecteplase (0.25mg/kg, maximum 25mg) before transfer or standard of care. A single bolus dose should be injected over 5 seconds.
This description comes directly from the study's public registry record.
Gaoting Ma, MD · +8683198082 · demo_doctor@163.com
Always discuss trial participation with your own doctor first.
| Xuanwu Hospital Capital Medical University | Beijing, Beijing Municipality, China | Recruiting |
| Affiliated Hospital of Shandong Second Medical University | Weifang, Shandong, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07253181