Condition: Autoimmune Rheumatologic Disease · Sponsor: University of Sao Paulo General Hospital
This clinical trial evaluates the immunogenicity (humoral and cellular) and safety of the 20-valent pneumococcal conjugate vaccine (PCV20) in children, adolescents, and young adults aged 2-25 years with autoimmune rheumatic diseases (ARDs). All participants will receive PCV20 according to prior vaccine history. Antibody titers, opsonophagocytic activity, cellular immune responses, and adverse events will be measured up to 6 months post-vaccination. Effects of immunosuppressive therapy and physical activity levels related vaccine response will also be assessed.
This description comes directly from the study's public registry record.
Clovis A Silva, Full Professor · (11) 2661-6105 · reumatologia.fmusp@hc.fm.usp.br
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| Hospital das Clinics da Faculdade de Medicina da Universidade de Sao Paulo | São Paulo, São Paulo, Brazil | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07252791