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Study identifier: NCT07252726 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Evaluating Dose Timing (Morning vs Evening) of Endocrine-based Therapies in Metastatic Breast and Prostate Cancers

Condition: Metastatic Breast Cancer · Metastatic Prostate Cancer  ·  Sponsor: Ottawa Hospital Research Institute

PhasePhase 4
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The REaCT-CHRONO-MetBP Pilot study will compare morning and evening administration of endocrine-based therapy in metastatic breast and prostate cancers. Participants with metastatic breast or prostate cancer will be randomly placed in one of two groups: a morning group and an evening group. The group assignment will determine whether they take their endocrine therapy in the morning or the evening. The primary outcome of this pilot study is to evaluate the feasibility of study procedures in order to conduct a larger definitive trial in the future. The secondary outcomes include comparing quality of life, tolerability, and efficacy outcomes between the morning and evening groups for each of the two cancer cohorts (metastatic breast and prostate cancer).

This description comes directly from the study's public registry record.

Talk to the study team

Lisa Vandermeer, MSc  ·  613-737-7700  ·  lvandermeer@ohri.ca

Deanna Saunders, MSc  ·  613-737-7700  ·  dsaunders@ohri.ca

Always discuss trial participation with your own doctor first.

Locations (3)

Waterloo Regional Health NetworkKitchener, Ontario, CanadaRecruiting
The Ottawa Hospital Cancer CentreOttawa, Ontario, CanadaRecruiting
Saskatoon Cancer CentreSaskatoon, Saskatchewan, CanadaNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07252726