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Study identifier: NCT07250854 Synced from ClinicalTrials.gov · July 29, 2026
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The Use of Near-Infrared Fluorescence Cholangiography With Indocyanine Green (ICG) in the Work Up of Neonatal Cholestasis

Condition: Biliary Atresia · Kasai · Cholestasis in Newborn  ·  Sponsor: University of Alabama at Birmingham

PhaseEARLY_Phase 1
Planned participants15
Who can joinAll sexes, 2 Weeks to 4 Months
Healthy volunteersYes

About this study

In infants that present with findings concerning for biliary atresia, along with other cholestatic work up which is standard, they will receive a one-time intravenous (IV) dose of Indocyanine Green (ICG). The infant's diapers will subsequently be examined for presence of the ICG, and if present, suggests bile flow. This was described as 97% accurate for assessing biliary patency and we would like to perform a similar study to assess biliary patency in the work up of neonatal cholestasis.

This description comes directly from the study's public registry record.

Talk to the study team

Samuel Hagman, DO, DO  ·  2056389801  ·  sehagman@uabmc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of Alabama At BirminghamBirmingham, Alabama, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07250854