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Study identifier: NCT07250646 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

A Study of Rebecsinib for Patients With Relapsed/Refractory Secondary Acute Myeloid Leukemia or High Risk Myelofibrosis

Condition: Secondary AML · Myelofibrosis  ·  Sponsor: Aspera Biomedicines, Inc.

PhasePhase 1
Planned participants28
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The purpose of this study is to test the safest and most effective dose of a new investigational drug, rebecsinib. Participants in this study will have either Secondary Acute Myeloid Leukemia (sAML) that has either returned (relapsed) or not responded to treatment (refractory) or have higher risk Myelofibrosis (MF). Participants will receive a study drug infusion on Day 1, Day 4, Day 8 and Day 11 of each 28-day cycle for a total of 6 cycles.

This description comes directly from the study's public registry record.

Talk to the study team

Curis L Scribner, MD  ·  510-914-8368  ·  cscribner@asperabio.com

Karla Mack  ·  443-253-0645  ·  kmack@asperabio.com

Always discuss trial participation with your own doctor first.

Locations (3)

City of Hope CenterDuarte, California, United StatesRecruiting
UC Davis Comprehensive Cancer CenterSacramento, California, United StatesRecruiting
UC San Diego Moores Cancer CenterSan Diego, California, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07250646