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Study identifier: NCT07250386 Synced from ClinicalTrials.gov · July 27, 2026
● Recruiting

A Study of CEA-Targeted CAR-T Therapy in Patients With CEA-Positive Advanced Solid Tumors

Condition: NSCLC (Advanced Non-small Cell Lung Cancer) · Breast Cancer  ·  Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

PhasePhase 1
Planned participants48
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This study is a single-arm, open-label, dose-escalating + dose-expansion clinical study, aiming to evaluate the safety and efficacy of CEA-targeted CAR-T cell preparations, and to preliminarily observe the study drug in CEA-positive advanced malignant tumors. The pharmacokinetic characteristics of CAR-T cell preparations for the treatment of patients with CEA-positive advanced malignancies were obtained and the recommended dose and infusion schedule.

This description comes directly from the study's public registry record.

Talk to the study team

Fuming Qiu, PhD  ·  +86 13858005908  ·  qiufuming@zju.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

The Second Affiliated Hospital, Zhejiang University School of MedicineHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07250386