← Eichor
Study identifier: NCT07248280 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Adding Aprepitant to a Multimodal Strategy for the Prevention of Postoperative Nausea and Vomiting in High-risk Outpatient Surgical Patients

Condition: Nausea and Vomiting, Postoperative · Prevention  ·  Sponsor: Centre hospitalier de l'Université de Montréal (CHUM)

PhasePhase 3
Planned participants260
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

Postoperative nausea and vomiting (PONV) are a frequent and debilitating complications after surgery, affecting up to 80% of patients at high risk in the absence of prophylaxis. Despite the rigorous application of the recommendations from the American Society of Anesthesiologists (ASA) at CHUM, a recent local study reveals a prevalence of 25% PONV at home after outpatient surgery. However, the therapeutic options at home remain limited. This study aims to evaluate if the addition of 40 mg aprepitant to a multimodal strategy for preventing PONV improves clinical outcomes in high-risk patients undergoing outpatient surgery.

This description comes directly from the study's public registry record.

Talk to the study team

Maxim Roy, MD, FRCPC  ·  514-890-8000  ·  maxim.roy.med@ssss.gouv.qc.ca

Vicky Thiffault, BSN  ·  514-890-8000  ·  anesthesie.recherche.chum@ssss.gouv.qc.ca

Always discuss trial participation with your own doctor first.

Locations (1)

Centre hospitalier de l'Université de Montréal (CHUM)Montreal, Quebec, CanadaRecruiting

Follow this study

Get one email when the public record changes — results posted, or the study's status changes. Nothing else, ever.

We email about this public record only. Unsubscribe anytime with one click. Never medical advice.

Is this your study? This page was generated automatically from the public registry record. Sponsors can claim it — free — to add branding and verified contact routing. Claim this page →

This page is independently generated by Eichor from the public ClinicalTrials.gov record and re-synced daily. It is not the sponsor's official website unless claimed. Nothing here is medical advice; eligibility is always determined by the study team — talk to your own doctor first.

Source record: clinicaltrials.gov/study/NCT07248280