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Study identifier: NCT07248072 Synced from ClinicalTrials.gov · July 28, 2026
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Effect of iPACK and BiFeS Blocks on Quality of Recovery After Total Knee Arthroplasty

Condition: Knee Osteoarthritis · Postoperative Pain Management · Total Knee Arthroplasty  ·  Sponsor: Ataturk University

PhaseNA
Planned participants74
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This prospective, randomized, double-blind clinical trial aims to compare the effects of two different posterior knee analgesia techniques-iPACK block (Interspace Between the Popliteal Artery and the Capsule of the posterior Knee) and the Biceps Femoris Short Head (BiFeS) block-when combined with an adductor canal block (ACB) in patients undergoing elective unilateral total knee arthroplasty (TKA). Effective postoperative analgesia is essential for early mobilization, enhanced recovery, and patient satisfaction after TKA. Although ACB provides good anterior knee analgesia while preserving quadriceps strength, additional posterior knee analgesia is often required. The iPACK block is a commonly used technique that targets the posterior knee capsule, whereas the newer BiFeS block aims to provide more selective posterolateral sensory blockade with potentially reduced risk of motor involvement. However, comparative clinical data between these two techniques are limited. The primary objective of this study is to evaluate the difference between the iPACK and BiFeS blocks in terms of Quality of Recovery-15 (QoR-15) scores at 24 hours postoperatively. Secondary objectives include comparisons of postoperative pain scores, opioid consumption, time to first analgesic request, quadriceps and anterior tibialis muscle strength, functional test performance, time to mobilization, active range of motion, and the incidence of adverse events. A total of 74 adult patients scheduled for electiv…

This description comes directly from the study's public registry record.

Talk to the study team

Ahmet Murat Yayık, Associate Professor  ·  +90-554-425-92-87  ·  m_yayik@hotmail.com

Mehmet Akif Yılmaz, assistant doctor  ·  +90-534-653-35-39  ·  mehmetakifyilmaz025@gmail.com

Always discuss trial participation with your own doctor first.

Locations (1)

Ataturk UniversityErzurum, Turkey (Türkiye)Recruiting

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Source record: clinicaltrials.gov/study/NCT07248072