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Study identifier: NCT07247188 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of a Single Dose of a 21-valent Pneumococcal Conjugate Vaccine in Children and Adolescents With Sickle Cell Disease

Condition: Sickle Cell Disease  ·  Sponsor: Sanofi

PhasePhase 3
Planned participants100
Who can joinAll sexes, 2 Years to 17 Years
Healthy volunteersNo

About this study

The purpose of this study is to measure whether PCV21 vaccine (investigational pneumococcal vaccine) is safe and can help the body to develop germ-fighting agents called "antibodies" (immunogenicity) compared with 20vPCV (licensed pneumococcal vaccine) when given as a single dose to children aged 2 to 17 years with sickle cell disease who had received or not a previous vaccination with pneumococcal conjugate or pneumococcal polysaccharide vaccine.

This description comes directly from the study's public registry record.

Talk to the study team

Trial Transparency email recommended (Toll free number for US & Canada)  ·  800-633-1610  ·  contact-us@sanofi.com

Always discuss trial participation with your own doctor first.

Locations (7)

Site # 8400006Atlanta, Georgia, United StatesRecruiting
Site # 8400002Atlanta, Georgia, United StatesRecruiting
Site # 8400003Omaha, Nebraska, United StatesRecruiting
Site # 8400001New Brunswick, New Jersey, United StatesRecruiting
Site # 8400004Houston, Texas, United StatesRecruiting
Site # 2140001Santo Domingo, Dominican RepublicRecruiting
Site # 2140003Santo Domingo, Dominican RepublicRecruiting

Follow this study

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Source record: clinicaltrials.gov/study/NCT07247188