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Study identifier: NCT07247058 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)

Condition: Mild Autonomous Cortisol Secretion (MACS)  ·  Sponsor: Johns Hopkins University

PhasePhase 4
Planned participants10
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

To characterize the impact of Isturisa on clinical features and comorbidities associated with MACS. The investigators hypothesize that patients treated with Isturisa will exhibit significantly better metabolic indicators (such as fasting glucose, HbA1c, and lipid profile), blood pressure, weight, body composition and bone mineral density than at Baseline. The investigators also assess the effect of Isturisa on quality of life and psychological symptoms in patients with MACS. The investigators hypothesize that treatment with Isturisa will lead to significant improvements in quality-of-life scores and reductions in depression scores compared to Baseline.

This description comes directly from the study's public registry record.

Talk to the study team

Pooneh Jabbaripour Sarmadian, MD  ·  667-208-8367  ·  pjabbar1@jh.edu

Tony Keyes  ·  410-550-6259  ·  akeyes1@jhmi.edu

Always discuss trial participation with your own doctor first.

Locations (1)

Johns Hopkins University School of MedicineBaltimore, Maryland, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07247058