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Study identifier: NCT07246304 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

TC-D101 Cell Therapy for Patients With DLL3-Positive SCLC

Condition: Small Cell Lung Cancer ( SCLC ) · CAR-T Cell Therapy  ·  Sponsor: TCRCure Biopharma Ltd.

PhaseEARLY_Phase 1
Planned participants24
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is a single-arm, open-label, dose-escalation clinical trial designed to evaluate the safety, tolerability, expansion, and persistence of TC-D101 CAR-T cells in patients with DLL3-positive Relapsed/Refractory primary small cell lung cancer(r/r SCLC) who have progressed after prior therapies. The primary objective is to determine the maximum tolerated dose (MTD), with a secondary aim to assess preliminary clinical efficacy in SCLC.

This description comes directly from the study's public registry record.

Talk to the study team

Tangfeng LV  ·  +862580863234  ·  njzyjg80863256@163.com

Always discuss trial participation with your own doctor first.

Locations (1)

The Jinling HospitalNanjing, Jiangsu, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07246304