Condition: Rheumatoid Arthritis (RA) · Sponsor: Sunnybrook Health Sciences Centre
People living with rheumatoid arthritis (RA) often experience flares-periods where their symptoms suddenly get worse. These flares can cause significant pain, make it harder to move and do daily activities, and lower overall quality of life. Doctors often treat flares with medications called glucocorticoids (GCs), which reduce inflammation. These medications can be taken by mouth (oral/PO) or given as a single injection into the muscle (intramuscular/IM). However, it's not clear which option works better from the patient's point of view-especially when it comes to relief of symptoms, improvements in function, and satisfaction with treatment. Most research so far has focused on how well the drugs control the disease, rather than how they impact the patient's overall experience. Research Questions: 1. Does a single GC injection work just as well as taking pills over a few weeks in improving symptoms reported by patients? 2. How do the two treatments compare in terms of symptom relief, ability to function, and patient satisfaction? 3. What do patients think and feel about using GCs to treat RA flares? What the Investigators Think: The investigators believe that a one-time GC injection is just as good as taking pills for a few weeks when it comes to managing RA flares. In fact, the injection might even be safer and preferred by patients. What the Investigators are Doing: The investigators will study 220 adults with RA who are currently having a flare (with at least 3 swolle…
This description comes directly from the study's public registry record.
Timothy S.H. Kwok, MD, MSc, FRCPC · 416-480-4580 · timothysh.kwok@utoronto.ca
Bindee Kuriya, MD, SM, FRCPC · (416) 586-4800 · bindee.kuriya@sinaihealth.ca
Always discuss trial participation with your own doctor first.
| Sunnybrook Health Sciences Centre | Toronto, Ontario, Canada | Recruiting |
| St. Michael's Hospital | Toronto, Ontario, Canada | Recruiting |
| Women's College Hospital | Toronto, Ontario, Canada | Recruiting |
| Toronto Western Hospital | Toronto, Ontario, Canada | Recruiting |
| Mount Sinai Hospital | Toronto, Ontario, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07245732