Condition: Inflammatory Bowel Disease (IBD) · Crohn Disease (CD) · Ulcerative Colitis (UC) · Sponsor: TIDHI Innovation Inc.
The SHIFT-IBD Study is being conducted at multiple medical centers across Canada to evaluate how well guselkumab (Tremfya) works for people with inflammatory bowel disease (IBD) who haven't responded well enough to ustekinumab. Patients will begin guselkumab based on their doctor's decision. If eligible, they may be invited to participate in the study, which involves monitoring symptoms, test results, and overall health over the course of one year. Guselkumab will be given according to local medical guidelines. Doctors can adjust the treatment as needed, just like in routine care. Researchers believe that switching to guselkumab may be as effective as other advanced treatments. For those who saw some improvement on ustekinumab but not enough, guselkumab may offer better symptom control-without worsening results on medical tests like endoscopy. The goal is to explore better treatment options for people whose IBD has not been well controlled with current therapies.
This description comes directly from the study's public registry record.
Ajani Jeyakumar, HBSc BScN RN · 647-812-2113 · ajeyakumar@tidhi.ca
Katy Staikin, MSc · 647-812-2113 · kstaikin@tidhi.ca
Always discuss trial participation with your own doctor first.
| University of Calgary | Calgary, Alberta, Canada | Recruiting |
| MA MacMillan | Fredericton, New Brunswick, Canada | Recruiting |
| Hamilton Health Sciences Corporation | Hamilton, Ontaio, Canada | Not Yet Recruiting |
| Barrie GI Associates | Barrie, Ontario, Canada | Recruiting |
| Brampton Gastroenterology Research Group Inc | Brampton, Ontario, Canada | Recruiting |
| GNRR Digestive Clinics and Research Center Inc. | Brampton, Ontario, Canada | Recruiting |
| LDDI Clinical Trials Inc. dba London Digestive Disease Institute | London, Ontario, Canada | Recruiting |
| West Gta Research Inc. | Mississauga, Ontario, Canada | Recruiting |
| Abp Research Services Corporation | Oakville, Ontario, Canada | Recruiting |
| Taunton Surgical Center | Oshawa, Ontario, Canada | Recruiting |
| Toronto Immune and Digestive Health Institute | Toronto, Ontario, Canada | Recruiting |
| The Research Institute of the McGill University Health Centre | Montreal, Quebec, Canada | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07245394