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Study identifier: NCT07245368 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of PRA-216 in Healthy Participants and Participants With Mild-to-Moderate Asthma

Condition: Mild to Moderate Asthma  ·  Sponsor: Prana Therapies Inc

PhasePhase 1/Phase 2
Planned participants96
Who can joinAll sexes, 18 Years to 65 Years
Healthy volunteersYes

About this study

Phase 1 of this study will consist of 2 parts * Part 1 will evaluate the safety, tolerability, pharmacokinetics and immunogenicity of PRA-216 in healthy volunteers through single ascending dose administered by either intravenous (IV) or subcutaneous (SC). * Part 2 will evaluate the safety, tolerability, pharmacokinetics (PK) and immunogenicity of PRA-216 in healthy volunteers with repeat doses of multiple ascending dose administered subcutaneously. Phase 2a of this study is a randomized, double-blind, placebo-controlled study to investigate the efficacy, safety and immunogenicity of PRA-216 in participants with mild to moderate asthma. The dose of PRA-216 for this phase was determined from Phase 1.

This description comes directly from the study's public registry record.

Talk to the study team

Linear site contact  ·  +61 (0)8 6382 5110  ·  enquiries@linear.org.au

Always discuss trial participation with your own doctor first.

Locations (7)

Emertitus Research SydneyBotany, New South Wales, AustraliaNot Yet Recruiting
Emeritus Research CamberwellCamberwell, Victoria, AustraliaNot Yet Recruiting
LinearJoondalup, Western Australia, AustraliaNot Yet Recruiting
LinearNedlands, Western Australia, AustraliaRecruiting
PCRN Waikato, NawtonHamilton, Auckland, New ZealandNot Yet Recruiting
Pacific Clinical Research Network-AucklandTakapuna, Auckland, New ZealandNot Yet Recruiting
PCRN Wellington, EbdentownUpper Hutt, Auckland, New ZealandNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07245368