Condition: Nasal Polyps · Sponsor: Tongji Hospital
This study is designed to evaluate whether the addition of nasopharyngeal lymphoid tissue ablation to full-house endoscopic sinus surgery (ESS) provides superior control of nasal mucosa inflammation compared to full-house ESS alone in patients with nasal polyps. Thirty-two adult participants will be randomly assigned to undergo either full-house ESS only or full-house ESS combined with nasopharyngeal lymphoid tissue ablation. The primary outcome will be assessed through changes in inflammatory cell profiles at 1, 3, and 6 months postoperatively. Secondary outcomes include inflammatory cytokine levels, symptom scores, endoscopic findings, polyp recurrence rates, and safety measures.
This description comes directly from the study's public registry record.
Yin Yao · 86 15071077020 · Dr.yaoyin@hotmail.com
Xing-Liang Wu · 86 15131662389 · 15131662389@163.com
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| Tongji Hospital of Tongji Medical College of Huazhong University of Science and Technology | Wuhan, Hubei, China | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07245329