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Study identifier: NCT07245303 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neural Mechanisms of Light Driven Analgesia

Condition: Musculoskeletal Pain · Fibromyalgia · Healthy Controls Group - Age and Sex-matched  ·  Sponsor: University of North Carolina, Chapel Hill

PhaseNA
Planned participants60
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersYes

About this study

The goal of this study will be to understand the biological mechanisms that are responsible to light-driven analgesia. Light presented to the retina has been shown to have pain relieving properties in pre-clinical and clinical studies. In this study the investigators will evaluate the functional connectivity between subcortical visual areas and non-image forming brain areas that are involved in pain sensation. The investigators will also evaluate how three colored light stimuli presented to the retina results in changes in whole brain evoked activation patterns in participants with chronic musculoskeletal pain and in healthy controls. The investigators will also assess while brain evoked activation patterns in response to a pressure pain stimulus in the presence of three light stimuli in individuals with chronic musculoskeletal pain and healthy controls.

This description comes directly from the study's public registry record.

Talk to the study team

Matthew Mauck, MD, PhD  ·  919-966-5136  ·  matt_mauck@med.unc.edu

Always discuss trial participation with your own doctor first.

Locations (1)

University of North Carolina at Chapel HillChapel Hill, North Carolina, United StatesRecruiting

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Source record: clinicaltrials.gov/study/NCT07245303