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Study identifier: NCT07244328 Synced from ClinicalTrials.gov · July 29, 2026
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Exploratory Study of UX-GIP001 Cell Therapy in Adult Patients With Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy (MTLE)

Condition: Epilepsy · MTLE  ·  Sponsor: Second Affiliated Hospital, School of Medicine, Zhejiang University

PhaseEARLY_Phase 1
Planned participants6
Who can joinAll sexes, 18 Years to 75 Years
Healthy volunteersNo

About this study

This is an exploratory clinical trial (Protocol: UX-GIP001-101) investigating UX-GIP001 Injection, a novel cell therapy product consisting of human GABAergic interneuron progenitor cells (GIP), for treating adult patients with drug-resistant unilateral medial temporal lobe epilepsy (MTLE). The primary objective is to assess the safety, tolerability, and preliminary efficacy of UX-GIP001. This is an open-label, single-arm study. All enrolled participants will receive the active investigational cell therapy. Seizure frequency and safety parameters will be evaluated by comparing post-transplant outcomes to pre-transplant baselines.

This description comes directly from the study's public registry record.

Talk to the study team

Yang, Doctor  ·  +86 132 0571 6189  ·  12418578@zju.edu.cn

Always discuss trial participation with your own doctor first.

Locations (1)

Second Affiliated Hospital, School of Medicine, Zhejiang UniversityHangzhou, Zhejiang, ChinaRecruiting

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Source record: clinicaltrials.gov/study/NCT07244328