Condition: Hidradenitis Suppurativa · Sponsor: Takeda
Hidradenitis Suppurativa (HS) is a skin condition that causes deep, painful bumps on the skin. These bumps usually appear in an area where the skin rubs together. They start as small bumps but may become swollen and red over time. If they fill with pus, these lumps are called abscesses; these can also burst. Over time, the area can get scars and tunnels on or under the skin. Recent studies suggest that the condition may start when hair follicles become damaged and blocked. This impacts the skin and may activate the body's germ-fighting (immune) system. This allows bacteria to grow on the skin which worsens the condition and can cause abscesses. The main aims of this study are to learn how safe zasocitinib is, how well it works and how well adults with HS tolerate it compared with a placebo. The participants will receive the study treatment (either zasocitinib or placebo) for up to 4 months (16 weeks). The placebo looks like the zasocitinib capsule but does not have any medicine in it. After the first 4 months, all participants (also those who initially received placebo) will then receive zasocitinib for up to 8 months (36 weeks). During the study, participants will visit their study clinic 12 times.
This description comes directly from the study's public registry record.
Takeda Contact · +1-877-825-3327 · medinfoUS@takeda.com
Always discuss trial participation with your own doctor first.
| Mayo Clinic | Scottsdale, Arizona, United States | Not Yet Recruiting |
| Johnson Dermatology | Fort Smith, Arkansas, United States | Recruiting |
| First OC Dermatology Research | Fountain Valley, California, United States | Recruiting |
| Direct Helpers Research Center | Hialeah, Florida, United States | Not Yet Recruiting |
| Advanced Clinical Research Institute | Tampa, Florida, United States | Recruiting |
| Beth Israel Deaconess Medical Center | Boston, Massachusetts, United States | Not Yet Recruiting |
| Wayne State University | Detroit, Michigan, United States | Not Yet Recruiting |
| Hamzavi Dermatology | Fort Gratiot, Michigan, United States | Recruiting |
| StracSkin, PLLC | Greenland, New Hampshire, United States | Recruiting |
| Northwell Health Physician Partners | Lake Success, New York, United States | Not Yet Recruiting |
| Mount Sinai Doctors | New York, New York, United States | Not Yet Recruiting |
| Apex Clinical Research Center, LLC. | Mayfield Heights, Ohio, United States | Not Yet Recruiting |
+ 37 more locations — full list on the registry record.
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Source record: clinicaltrials.gov/study/NCT07244263