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Study identifier: NCT07243483 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of the Relationship Between the Pharmacokinetics (PK) and Pharmacodynamics of Venetoclax in Patients With Acute Myeloblastic Leukemia

Condition: Acute Myeloid Leukemia  ·  Sponsor: Centre Leon Berard

PhaseNA
Planned participants100
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is a prospective, multicenter, clinical-biological cohort study. Its objective is to assess the pharmacokinetics-pharmacodynamics (PK-PD) of venetoclax (VEN) in patients with Acute Myeloid Leukemia (AML). This study involves only minimal risks and constraints related to the collection of biological samples (blood samples for PK testing) and the collection of clinical data. Therapeutic management of patients participating in this study is not changed. A total of 100 patients will be included in the study over a 12-month period. A maximum of 21 additional samples are planned, with a maximum of 12 mL of blood per sampling day (4 mL at each sampling time) for PK dosing of venetoclax.

This description comes directly from the study's public registry record.

Talk to the study team

Michaël Philippe  ·  +33478782666  ·  michael.philippe@lyon.unicancer.fr

Amine Belhabri, MD  ·  amine.belhabri@lyon.unicancer.fr

Always discuss trial participation with your own doctor first.

Locations (5)

Centre Hospitalier Pierre OudotBourgoin, France, FranceRecruiting
CHU de GrenobleGrenoble, FranceRecruiting
Centre Leon BerardLyon, FranceRecruiting
CHU de Saint-ÉtienneSaint-Etienne, FranceRecruiting
Hôpitaux Nord-Ouest - Villefranche-sur-SaôneVillefranche-sur-Saône, FranceRecruiting

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Source record: clinicaltrials.gov/study/NCT07243483