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Study identifier: NCT07242742 Synced from ClinicalTrials.gov · July 29, 2026
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Effectiveness of Pulpotomy vs. Root Canal Treatment in Extremely Deep Caries

Condition: Extremely Deep Caries · Pulpitis  ·  Sponsor: National University Hospital, Singapore

PhaseNA
Planned participants93
Who can joinAll sexes, 12 Years to no upper limit
Healthy volunteersNo

About this study

Recent clinical trials comparing pulpotomy versus root canal treatment (RCT) have shown promising outcomes; however, the current evidence lacks generalisability to general practitioners. It remains to be elucidated whether these favourable results can be replicated in a primary care setting. This study aims to address that gap by involving senior dental students undergoing supervised university education and training, with the potential to inform future best practice guidelines and promote the adoption of vital pulp therapy (VPT) as a predictable treatment alternative in the general dental population. The clinical procedure involves complete caries-free excavation carried out under rubber dam isolation. After confirming vital pulp status-demonstrated by bleeding upon entry, participants will be randomised to receive one of two treatments: RCT or full pulpotomy. Outcomes will include clinical and radiographic success or failure of the intervention at 12 months. Additionally, patient-reported outcomes will be collected, specifically pain experienced and the use of analgesia during the immediate post-operative period (days 3 and 7).

This description comes directly from the study's public registry record.

Talk to the study team

Victoria Yu  ·  (65) 9004 1044  ·  denyshv@nus.edu.sg

Always discuss trial participation with your own doctor first.

Locations (1)

National University Centre For Oral Health Singapore (NUCOHS)Singapore, SingaporeRecruiting

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Source record: clinicaltrials.gov/study/NCT07242742