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Study identifier: NCT07242547 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Study of Tarlatamab as Maintenance Treatment After Chemo-radiotherapy for Limited Stage SCLC Patients

Condition: Limited-stage Small-cell Lung Cancer · Carcinoma, Small Cell Lung · Respiratory Tract Neoplasms  ·  Sponsor: Fundación GECP

PhasePhase 2
Planned participants37
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

This is an open-label, phase II, exploratory and multi-centre clinical trial. 37 Limited stage SCLC patients not eligible for concurrent chemo-radiotherapy will be enroll. Patients will be enrolled in the trial after receiving sequential chemo-radiotherapy, if there is no progression disease, patients will be treated with maintenance Tarlatamab. Patients will receive maintenance with Tarlatamab IV until disease progression unacceptable toxicity, patient or physician decision to discontinue or death. The primary objective is to evaluate the Progression free survival (PFS). Patient accrual is expected to be completed within 2 years. Treatment and follow-up are expected to extend the study duration to a total of 5 years. Patients will be followed for 2 years after enrollment. The study will end once survival follow-up has concluded.

This description comes directly from the study's public registry record.

Talk to the study team

Eva Pereira  ·  +34934302006  ·  gecp@gecp.org

Always discuss trial participation with your own doctor first.

Locations (20)

Hospital General Universitario de AlbaceteAlbacete, Albacete, SpainRecruiting
Hospital General Universitario Dr. Balmis de AlicanteAlicante, Alicante, SpainRecruiting
Hospital General Universitario de ElcheElche, Alicante, SpainRecruiting
Hospital de la Santa Creu i Sant PauBarcelona, Barcelona, SpainRecruiting
Hospital Universitari Vall d'HebronBarcelona, Barcelona, SpainRecruiting
Hospital Clínic de BarcelonaBarcelona, Barcelona, SpainRecruiting
Fundació AlthaiaManresa, Barcelona, SpainRecruiting
Hospital de BasurtoBilbao, Bizkaia, SpainRecruiting
Hospital Universitario de Jerez de la FronteraJerez de la Frontera, Cádiz, SpainRecruiting
Hospital Universitario Lucus AugustiLugo, Lugo, SpainRecruiting
Hospital Clínico San CarlosMadrid, Madrid, SpainRecruiting
Hospital Universitario Fundación Jiménez DíazMadrid, Madrid, SpainRecruiting

+ 8 more locations — full list on the registry record.

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Source record: clinicaltrials.gov/study/NCT07242547