Condition: Intensive Care Unit Sedation · Sedation · Target Controlled Infusion of Propofol · Sponsor: Hacettepe University
This prospective observational study aims to compare the clinical performance of two target-controlled infusion (TCI) models, Eleveld and Schnider, for propofol sedation in mechanically ventilated intensive care unit (ICU) patients. The study evaluates sedation depth, hemodynamic stability, and recovery profiles using the Bispectral Index (BIS) and Riker Sedation-Agitation Scale. Secondary outcomes include awakening time, total propofol dose, and incidence of delirium after sedation withdrawal. The findings may help identify the most reliable pharmacokinetic model for safe and effective ICU sedation.
This description comes directly from the study's public registry record.
DUYGU OZDEMIR SIMSEK, MD · +905372916432 · duyguozdemir94@gmail.com
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| Hacettepe University | Ankara, Turkey (Türkiye) | Recruiting |
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Source record: clinicaltrials.gov/study/NCT07239687