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Study identifier: NCT07239310 Synced from ClinicalTrials.gov · July 28, 2026
● Recruiting

Neuclare Device for Temporary Improvement of Executive Function in Patients With Mild Cognitive Impairment and Prodromal Alzheimer's Disease

Condition: Mild Cognitive Impairment · Alzheimer's Disease(AD)  ·  Sponsor: Deepsonbio

PhaseNA
Planned participants138
Who can joinAll sexes, 55 Years to 90 Years
Healthy volunteersNo

About this study

This study is a multicenter, randomized, double-blind, parallel-group, prospective confirmatory clinical trial designed to evaluate whether the Neuclare medical device can temporarily improve executive function (planning and problem-solving abilities) in adults with mild cognitive impairment or very early Alzheimer's disease. Participants will continue their current medication and be randomly assigned to receive either the Neuclare device (treatment group) or a sham device (control group). The device will be applied to the brain three times per week for four weeks. Both participants and study staff are blinded to the group assignment. Safety and adverse events will be closely monitored throughout the study. During the trial, assessments will include attention, cognitive function, daily living activities, brain imaging (Amyloid PET-CT), blood biomarkers, and quality of life (EQ-5D-5L). The goal of this study is to determine whether the Neuclare device, in combination with standard medication, can safely provide temporary improvements in executive function.

This description comes directly from the study's public registry record.

Talk to the study team

Sung Kyung Lee  ·  82+10-9877-8173  ·  sklee@deepsonbio.com

Always discuss trial participation with your own doctor first.

Locations (3)

Hallym University Dongtan Sacred Heart HospitalHwaseong-si, Gyeonggi-do, South KoreaNot Yet Recruiting
Seoul National University Bundang HospitalSeongnam-si, Gyeonggi-do, South KoreaRecruiting
Ewha Womans University Mokdong HospitalSeoul, South KoreaRecruiting

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Source record: clinicaltrials.gov/study/NCT07239310