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Study identifier: NCT07237373 Synced from ClinicalTrials.gov · July 29, 2026
● Recruiting

Percutaneous Thermo-ablation for the Treatment of Benign Thyroid Nodules

Condition: Benign Thyroid Nodule  ·  Sponsor: University Hospital, Ghent

PhaseN/A
Planned participants50
Who can joinAll sexes, 18 Years to no upper limit
Healthy volunteersNo

About this study

The goal of this observational study is to learn if radiofrequency ablation (RFA), a minimally invasive thermoablation technique, can safely reduce symptoms and improve quality of life in adults with symptomatic benign thyroid nodules or autonomously functioning thyroid nodules. The main questions it aims to answer are: * Does RFA improve health-related quality of life (HRQoL) as measured by the ThyPRO-39 questionnaire? * Does RFA effectively reduce nodule volume and related symptoms (compressive or cosmetic)? Participants will: * Undergo a radiofrequency ablation procedure of the thyroid nodule performed under ultrasound guidance in an outpatient setting. * Complete quality of life questionnaires (ThyPRO-39) before treatment and at follow-up visits. Attend follow-up visits at 1, 3, 6, and 12 months with: * Ultrasound assessments of the thyroid nodule * Symptom and cosmetic scoring * Blood tests to monitor thyroid function * Safety checks for possible complications

This description comes directly from the study's public registry record.

Talk to the study team

Charlotte Harth, MD  ·  +32 9 332 0450  ·  studies.vinrad@uzgent.be

Lien Van Cauwenberghe, MSc  ·  +32 9 332 0450  ·  lien.vancauwenberghe@uzgent.be

Always discuss trial participation with your own doctor first.

Locations (3)

AZ Sint-Jan BruggeBruges, BelgiumNot Yet Recruiting
UZ GentGhent, BelgiumRecruiting
UZ LeuvenLeuven, BelgiumNot Yet Recruiting

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Source record: clinicaltrials.gov/study/NCT07237373